Declines in Large Wildlife Lead to Increases in Disease Risk

UCSB professor’s research in East Africa shows biodiversity loss heightens the risk of disease transmission from animals to humans.

April 28, 2014
A plains zebra in front of the Kenya Long-Term Exclosure experiment.  Credit: Duncan Kimuyu
A plains zebra in front of the Kenya Long-Term Exclosure experiment. Credit: Duncan Kimuyu

In the Middle Ages, fleas carried by rats were responsible for spreading the Black Plague. Today in East Africa, they remain important vectors of plague and many other diseases, including Bartonellosis, a potentially dangerous human pathogen.

Research by Hillary Young, assistant professor in UC Santa Barbara’s Department of Ecology, Evolution and Marine Biology, directly links large wildlife decline to an increased risk of human disease via changes in rodent populations. The findings appear today in the Proceedings of the National Academy of Sciences Early Online Edition

With an East African savanna ecosystem as their research site, Young and her colleagues examined the relationship between the loss of large wildlife — defaunation — and the risk of human disease. In this case, they analyzed Bartonellosis, a group of bacterial pathogens which can cause endocarditis, spleen and liver damage and memory loss.